BST1 anticorps

N° du produit ABIN1105911

Cet anticorps anti-BST1 est un anticorps Souris Monoclonal détectant BST1 dans FACS. Adapté pour Humain.

Aperçu rapide pour BST1 anticorps (ABIN1105911)

Antigène: BST1 (Bone Marrow Stromal Cell Antigen 1 (BST1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BST1 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: RF3

Détail du produit anti-BST1 anticorps

Specificité: This antibody reacts with CD157 antigen. This antibody reacts with RASV5-5 cells, and does not react with a healthy donor-derived nonsupportive cell line, NFSV1-1.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Protein A agarose

Immunogène: RA-derived BM stromal cell line RASV5-5

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Prepare a stock solution by dissolving the lyophilized antibody in 100 μL of distilled water. After reconstitution, the IgG concentration will be 1 mg/mL.

Buffer: PBS ( pH 7.2), 0.09 % NaN3, 1 % sucrose

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.

Détails sur BST1

Antigène: BST1 (Bone Marrow Stromal Cell Antigen 1 (BST1))

Autre désignation: CD157 / BST1

Sujet: In the bone marrow (BM) hematopoietic microenvironment, stromal cells play crucial roles. Stromal cells secrete a variety of cytokines and express cell surface molecules that regulate the growth of hematopoietic cells. BM stromal cell lines derived from patients with rheumatoid arthritis (RA) have augmented ability to support the growth of a murine pre-B cell line, DW34. BST-1 (bone marrow stromal cell antigen-1) is expressed on BM stromal cell lines and is responsible for an augmented ability to support pre-B cell line growth. BST-1 is also expressed by RA-derived synovial cell lines, a myelomonocytic cell lines, and HUVEC, suggesting that BST-1 has other functional roles than just supporting pre-B cell growth.Synonyms: ADP-ribosyl cyclase 2, BST-1, Bone marrow stromal antigen 1, Cyclic ADP-ribose hydrolase 2, cADPr hydrolase 2

ID gène: 683

NCBI Accession: NP_004325

UniProt: Q10588